
产品货号:
Z17385
中文名称:
HDC抗体
英文名称:
Anti-HDC Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HDC Antibody |
指标别名 | HDC;Histidine decarboxylase |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,IHC,WB |
基因名称 | HDC |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human HDC. |
计算分子量 | 74KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | HDC(Histidine decarboxylase) is the enzyme that catalyzes the reaction that produces histamine from histidine with the help of vitamin B6.The HDC gene is mapped on 15q21.2.The deduced 662-amino acid protein has a molecular mass of 74,148 Da.The gene contains 12 exons spanning approximately 24kb.The biogenic amine histamine is an important modulator of numerous physiologic processes,including neurotransmission,gastric acid secretion,and smooth muscle tone.The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase.This homodimeric enzyme is a pyridoxal phosphate(PLP)-dependent decarboxylase and is highly specific for its histidine substrate.Ercan-Sencicek et al.noted that animal studies had shown that lack of Hdc in mice results in increased locomotor and stereotypic behaviors,as well as increased anxiety. |
Uniprot ID | P19113 |
基因名全称 | Histidine decarboxylase |
蛋白名全称 | Histidine decarboxylase |
推荐稀释比 | WB 1:500~1:2000 IHC-P 1:100~300 ELISA 1:20000 |
相关搜索:HDC抗体,HDC多抗,Anti-HDC Antibody