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所在位置:所有产品 > 抗体抗原 > 一抗 > HDC抗体
HDC抗体图片
产品货号:
Z17385
中文名称:
HDC抗体
英文名称:
Anti-HDC Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-HDC Antibody
指标别名HDC;Histidine decarboxylase
克隆性Polyclonal
检验物种human,mouse,rat
应用范围ELISA,IHC,WB
基因名称HDC
抗体来源Rabbit
抗体类型IgG
免疫原Synthesized peptide derived from human HDC.
计算分子量74KD
成分Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料HDC(Histidine decarboxylase) is the enzyme that catalyzes the reaction that produces histamine from histidine with the help of vitamin B6.The HDC gene is mapped on 15q21.2.The deduced 662-amino acid protein has a molecular mass of 74,148 Da.The gene contains 12 exons spanning approximately 24kb.The biogenic amine histamine is an important modulator of numerous physiologic processes,including neurotransmission,gastric acid secretion,and smooth muscle tone.The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase.This homodimeric enzyme is a pyridoxal phosphate(PLP)-dependent decarboxylase and is highly specific for its histidine substrate.Ercan-Sencicek et al.noted that animal studies had shown that lack of Hdc in mice results in increased locomotor and stereotypic behaviors,as well as increased anxiety.
Uniprot IDP19113
基因名全称Histidine decarboxylase
蛋白名全称Histidine decarboxylase
推荐稀释比WB 1:500~1:2000
IHC-P 1:100~300
ELISA 1:20000

相关搜索:HDC抗体HDC多抗Anti-HDC Antibody
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